INPHOG-ALL-24-03

Improving Survival in Childhood Acute Lymphoblastic Leukemia in India (ISCALL): ICiCLE Implementation Study.

PI : Dr. Venkatraman Radhakrishnan

Institution : Cancer Institute Adyar, Chennai

About the Study

This collaborative multicentre national study is designed for patients newly diagnosed with Acute Lymphoblastic Leukemia (ALL) across participating centres in India. The study aims to strengthen standardized treatment delivery, improve clinical data collection, and evaluate treatment outcomes in the Indian setting. By bringing together multiple institutions under a common framework, the study seeks to enhance uniformity in diagnosis, risk stratification, treatment monitoring, and supportive care practices for ALL patients.

Aim of the Study

To improve treatment outcomes and survival in newly diagnosed patients with Acute Lymphoblastic Leukemia (ALL) through collaborative multicentre participation, standardized treatment approaches, and systematic clinical data collection across India.

Eligibility Criteria

Inclusion Criteria

Patients with newly diagnosed Acute Lymphoblastic Leukemia (ALL).
Patients registered and treated at participating study centres.
Availability of required baseline diagnostic and clinical evaluation details as per study protocol.
Provision of informed consent/assent as applicable.

Exclusion Criteria

Patients previously treated for ALL beyond emergency or pre-phase therapy.
Patients unwilling or unable to comply with study-related treatment or follow-up requirements.
Patients not fulfilling protocol-defined eligibility criteria at participating centres.